Project 3 Team Members

Project Lead: Deirdre R. Meldrum

  • Deirdre R. Meldrum is ASU Senior Scientist, Director of the Biosignature Initiative and Director of the Center for Biosignature Discovery Automation (CBDA) in the Biodesign Institute and Professor of Electrical Engineering in the School of Electrical, Computer, and Energy Engineering. She is also Director and Principal Investigator of the NIH Center of Excellence in Genomic Sciences: Microscale Life Sciences Center (MLSC). Her research interests include probing heterogeneity by live single cell analyses, nuclear organization in cancer, microscale systems for biological applications, robotics and control systems for applications to human health and disease and the oceans. She served on the National Advisory Council for Human Genome Research. More Info

  • Team Members

  • Roger H. Johnson is a Research Scientist and Laboratory Manager in the Center for Biosignatures Discovery Automation in ASU’s Biodesign Institute. Roger is responsible for overall management of daily research activities in the Center, and leads the cell CT research. He has over twenty years’ experience in 3D micro CT, and is an expert in CT scanner design and construction, image reconstruction algorithms, and 3D image processing and analysis. Roger is co-inventor of the cell CT and has seven patents including two on x-ray and two on optical microtomography.

  • Laimonas Kelbauskas is an Assistant Research Professor in the Center for Biosignatures Discovery Automation. He has an PhD in physics and his major research interests are in methods for early cancer detection, the role of intercellular interactions and cell-to-cell variability in pre-neoplastic to neoplastic progression, and changes in gene transcription levels in individual cells in carcinogenesis.

  • Brain Ashcroft received his PhD in physics from ASU for his work on fast DNA sequencing with an AFM/rotaxane system. He worked as a postdoctoral scholar at Leiden university for three years where he explored growth disorders with nanoindention. In addition, he worked on a microfluidics system to do cancer detection and monitoring from blood plasma, and studied the formation of scars in heart tissue. He is currently a postdoctoral scholar at the Center for Biosignatures Discovery Automation. His research is focused on software development for high quality 3D reconstructions in absorption and fluorescent modalities with fixed and live cells.

  • Thai Tran received his Ph.D. in molecular biology from Purdue University and was trained a as a postdoctoral fellow with Dr. Hallgeir Rui at the Kimmel Cancer Center, Thomas Jefferson University. Dr. Tran has background in molecular and cellular biology of cancer. His research focus is to investigate the molecular functions that govern cancer cell development and progression.

  • Jiangxin Wang received a Ph.D. in molecular genetics. Currently he is an assistant research scientist for the Center for Biosignatures Discovery Automation at the Biodesign Institute at Arizona State University. His research interests include single cell transcriptomics, live single cell analyses, and gene signatures as prognostic markers in diseases.

  • Kimberly J. Bussey is an Assistant Professor in the Clinical Translational Research Division of the Translational Genomics Research Institute (TGen), Co-Director of the Adrenocortical Carcinoma Research Program at TGen, and an Adjunct Associate Research Scientist with the Center for Biosignatures Discovery Automation at the Biodesign Institute at Arizona State University. Her research interests lie in exploiting intra-tumor heterogeneity in cancer for treatment. Dr. Bussey has a background in medical and molecular genetics, rare tumors, cancer cytogenetics, and applied bioinformatics.

  • Vivek Nandakumar is a graduate research associate at the Center for Biosignatures Discovery Automation in the biodesign institute. His research is centered around quantitative three-dimensional morphometric biosignatures for early cancer detection using the Cell-CT.

  • Kathryn Hernandez is an undergraduate research assistant at the Center for Biosignatures Discovery Automation. She is a senior majoring in Biological Sciences at Arizona State University and has extensive prior work experience in clinical and reference laboratories. She works on single cell imaging with Cell-CT.

  • Miranda Slaydon is an undergraduate majoring in Geology. She assists with sample preparation and imaging for Cell-CT

  • Stephanie Helland is an undergraduate student worker at CBDA. She is a sophomore at ASU pursuing bachelor of science degrees in Biochemistry and Molecular Biosciences. She assists with sample preparation and imaging for Cell-CT

  • Beatriz Rodolpho is a visiting scholar at the Center for Biosignatures Discovery Automation in the Biodesign Institute. She is currently pursuing her MS degree at Universidade Nova de Lisboa in Portugal. Her research includes Cell-CT imaging and development of metrics to assess quality of 3D reconstruction algorithms.

Leave a Reply