August 25


Biodesign Auditorium
727 E. Tyler St. Tempe
AZ 85287

There are approximately 16,000 cases of esophageal cancer each year in the United States and sadly, most patients die.. In contrast to the United States where adenocarcinoma is the primary histologic cause of cancer, worldwide, squamous cell carcinoma accounts for more than 80{236bd5e292587b885399ce1fe93b84c86ca4f34851d3c4bf06f3f0da35a3ccbb} of cases.
With both types of histology, the prognosis and survival are linked closely to the stage at which the diagnosis is made. Therefore, for patients who present with symptoms of difficulty swallowing or weight loss, the cancer is usually advanced and the survival is less than 10{236bd5e292587b885399ce1fe93b84c86ca4f34851d3c4bf06f3f0da35a3ccbb}. If it were possible to detect cancer in an earliest stage (for example stage I) or if a precursor lesion could be discovered, the survival would improve dramatically; if precursor lesions are discovered, survival can be more than 95{236bd5e292587b885399ce1fe93b84c86ca4f34851d3c4bf06f3f0da35a3ccbb}.
There has been a great interest in the United States and other parts of the world for non-surgical endoscopic techniques such as endoscopic mucosal resection or ablation to manage and eliminate early esophageal cancers. Results from some of these studies will be discussed.
The collaborations between Mayo Clinic and Arizona State University provide an exciting opportunity for advances to diagnose, manage and ultimately prevent esophageal cancer.