April 5th


Biodesign Auditorium
727 E. Tyler St. Tempe
AZ 85287

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The major recent advances in genomic sequencing provide unparalleled opportunities to identify novel mechanisms that regulate susceptibility to human diseases, as well as disease pathogenesis and progression. However, the heterogeneity of human populations leads to complexity that complicates these analyses. Here, we will discuss clinical conundrums of human adaptation to extreme environments, and the impact of tumor heterogeneity on clinical prognoses, for which genetic profiling has uncovered unique and targetable pathways to improve patient outcomes.