Initiation of Micro-Metastases from Low-Fitness Cancer Cells: Rare, Explosive, and Deterministic

PS-OC archive seminars

September 22 2011 Biodesign Auditorium 727 E. Tyler St. Tempe AZ 85287 View Web Cast Video The final stage of the metastatic cascade, colonization of secondary tissue sites, is very hard to address experimentally and is thus poorly understood. Given the long...

The Role of Epigenetic Alterations in Colon Cancer

PS-OC archive seminars

October 10 2011 Biodesign Auditorium 727 E. Tyler St. Tempe AZ 85287 View Web Cast Video Colorectal cancer arises as the consequence of the accumulation of genetic alterations (e.g. gene mutations, gene amplification, etc.) and epigenetic alterations (e.g. aberrant...

Discovery of Prolactin Signaling Pathway in Breast Cancer

PS-OC archive seminars

October 20 2011 Biodesign Auditorium 727 E. Tyler St. Tempe AZ 85287 View Web Cast Video Breast cancer is the second leading cause of deaths among women. In the United States, an estimated 230,480 are diagnosed with breast cancer each year and, of these, 39,520 are...

How Endothelial Cells Regulate Leukocyte Transmigration: Application to Cancer Metastasis

PS-OC archive seminars

November 3 2011 Biodesign Auditorium 727 E. Tyler St. Tempe AZ 85287 View Web Cast Video Speaker: William Muller, MD, PhD. received his A.B. degree summa cum laude from Harvard University in 1975. He earned his PhD degree from The Rockefeller University in 1981 under...

Target Identification in Cancer Using RNA interference – Accelerated Therapy Development in Leukemias

PS-OC archive seminars

November 17 2011 Biodesign Auditorium 727 E. Tyler St. Tempe AZ 85287 The challenge in drug development has been the implementation of novel active treatment regimens in cancer. Despite a deeper understanding of molecular oncogenesis many therapeutic strategies have...
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