Profile of Zachary Compton

Profile of Zachary Compton

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Read this great profile of post-doctoral ACE researcher, Zach Compton.  Zach is now at the University of Arizona.  We are so proud of Zach!
The relationship between diet, plasma glucose, and cancer prevalence across vertebrates

The relationship between diet, plasma glucose, and cancer prevalence across vertebrates

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In this intriguing research paper, recently published in Nature Communications, ACE researchers led by Stefania E. Kapsetaki and Carlo Maley show that, surprisingly, there is no significant link between diet and plasma sugar levels across nonhuman vertebrate species,...
Ancient sea creatures offer fresh insights into cancer  Sponges withstand extreme radiation, provide clues to disease resistance

Ancient sea creatures offer fresh insights into cancer Sponges withstand extreme radiation, provide clues to disease resistance

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Ace researchers have found that sea sponges are incredibly resistant to radiation, and though some species can live for hundreds of years or longer, the their study didn’t find any evidence of tumors in the animals. In fact, one species studied could withstand...
New study explores cancer prevalence in hundreds of vertebrate species

New study explores cancer prevalence in hundreds of vertebrate species

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In a major study of almost 300 vertebrate species published in the journal, Cancer Discovery, ACE researchers examined over 16,000 necropsy records to look for the incidence of cancer across species.  Among the findings of this ten year study, the team discovered that...

Testing Adaptive Therapy Protocols Using Gemcitabine and Capecitabine in a Preclinical Model of Endocrine-Resistant Breast Cancer

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The biggest obstacle to curing cancer is the fact that cancers often harbor resistant cells that are unaffected by cancer drugs. A team that includes several ACE researchers tested a new strategy, called adaptive therapy, for maintaining control over resistant cells...
Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria

Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria

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Cancer in elephants is very rare, and in order to understand just how they are protected from the disease despite their size and long lifespan, a team including ACE researchers studied their TP-53 genes. Their results appeared in Nature, Cell Death Discovery in...
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