Litter size relates to cancer risk; body mass and longevity do not
Why are some species of mammals more vulnerable to cancer than others? It’s an important question since the answers may guide us to new understandings of cancer development in humans. In a careful analysis of 42 years of necropsy data from San Diego Zoo and...
Bird size with dinosaur-level cancer defences: can evolutionary lags during miniaturisation explain cancer robustness in birds?
Fascinating preprint by ACE members E. Yagmu Erten, Marc Tollis, Hanna Kokko: https://www.biorxiv.org/content/10.1101/2020.10.22.345439v1 An increased appreciation of the ubiquity of cancer risk across the tree of life means we also need to understand the more robust...
When, why and how clonal diversity predicts future tumour growth – New research paper from ACE team member, Rob Noble
First published: 04 July 2020 in Evolutionary Applications https://doi.org/10.1111/eva.13057 Authors: Robert Noble, John T Burley, Cécile Le Sueur, Michael E Hochberg Intratumour heterogeneity holds promise as a prognostic biomarker in multiple cancer types. However,...
Endless Forms Most Beautiful: A Garden Shows That Cancer Is a Part of Life
Published on-line in Leonardo on March 16 2020. Pamela Winfrey, Caspian Robertson, Carlo Maley and Athena Aktipis. Endless Forms Most Beautiful is a crested cactus garden that embodies both an aesthetic and medically transformative approach to cancer. The cacti in...
The Evolution of Human Cancer Gene Duplications across Mammals – Preprint
New study sheds light on many aspects of the evolution of cancer suppression in mammals. Published in bioRxiv (the preprint server for biology) on March 5 2020. Marc Tollis, Aika K. Schneider-Utaka, Carlo C. Maley. Abstract Cancer is caused by genetic alterations that...
