Research Papers

Reuniting philosophy and science to advance cancer research

The use of philosophical methods to pin down definitions and conceptualizations in cancer research could help sort out the wooly thinking that is pervasive in the subject and help scientists from different disciplines to better collaborate, argues a discussion paper...

ACE Scholars Program – a Big Success!

ACE Scholars Program – a Big Success!

We are so proud of our ACE Scholars! They are undergraduates in many disciplines who come from all around the nation to help us understand the evolution and control of cancer.  The students devote hours each week to the program, working individually and then meeting ...

The need for evolutionary theory in cancer research

This easy to read article by ACE's Amy M. Boddy, just published in European Journal of Epidemiology (2022), argues that even if we could  understand all the mechanisms for cells to turn cancerous, it wouldn't be enough to help us treat and avoid the disease.   For...

ACE Research paper in the journal Nature

Phenotypic plasticity and genetic control in colorectal cancer evolution is the second article by ACE researchers published in Nature on 26 October 2022.  Here they show that genetic variation within a colorectal tumor doesn't often affect gene expression traits and...

Remarkable study by ACE researchers just published in Nature

The co-evolution of the genome and epigenome in colorectal cancer Published on 26 October 2022 in the journal Nature, this groundbreaking study by ACE researchers and their colleagues shows the interaction of genetic and epigenetic changes in tissue taken from...

Cancer Garden creation described in ‘Leonardo’

A paper describing the background to the creation of Endless Forms Most Beautiful, the cancer cactus garden at Arizona State University, has appeared in the arts/science journal, Leonardo.  Read about the unique collaboration between of the landscape architect, the...

Most Tumors in Snakes are Cancerous

This study, A Multi-Institutional Collaboration to Understand Neoplasia, Treatment and Survival of Snakes, is just published in the journal Animals (January 21 2022).  Although snakes seem to have more tumors than other species of reptiles studied, nothing much is...

Spatial Structure Governs the Mode of Tumour Evolution

Spatial Structure Governs the Mode of Tumour Evolution

Knowing how tumors evolve would be very useful to clinicians trying to predict the spread of cancer and the likely success of different therapies.  New mathematical models developed by Robert Noble and his colleagues should...