News
Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria
Cancer in elephants is very rare, and in order to understand just how they are protected from the disease despite their size and long lifespan, a team including ACE researchers studied their TP-53 genes. Their results appeared in Nature, Cell Death Discovery in...
Is chimerism associated with cancer across the tree of life?
In this intriguing paper published in PLOS ONE in June 2023, ACE researchers and their colleagues studied the association between chimerism and cancer across the tree of life. A chimera is an organism has that has cells from two or more genetically distinct sources. ...
The evolutionary theory of cancer: challenges and potential solutions
In this Perspective article in Nature Reviews Cancer, Carlo Maley and his colleague, Lucie Laplane, point out that there is much yet to understand about the many theories and models of cancer evolution in order to discover the best way to treat and prevent the...
Cells eating other Cells – found across the tree of life!
In this fascinating study in Scientific Reports, ACE researchers, Stefania Kapsetaki (now at Tufts University), Luis H. Cisneros and Carlo Maley trawled the literature to discover that cell-on-cell cannibalism is a behavior that occurs in both cancer cells and normal...
Birds species that lay more eggs get more cancer
Bird species that have small clutches tend to get less cancer than species that have large clutches. That's the conclusion of an international team of scientists that includes several ACE researchers. The team studied the necropsy records of close to 6000 birds...
ACE sponsors science awards for local kids
One of the most enjoyable experiences of ACE this year was to judge the Chandler school district science prizes. ACE awarded prizes to children in the senior, junior and elementary divisions for their work concerning life sciences and cancer research. Congratulations to all the winners!
ACE at Spring Science Fairs
Once again, we attended the City of Chandler's Innovation Fair. The fair, in the center of town, attracted over 6000 visitors, mainly families, who came along to experience the excitement of the science taking place in Arizona's Valley of the Sun and explore its...
ACE Scholars Program – a Big Success!
We are so proud of our ACE Scholars! They are undergraduates in many disciplines who come from all around the nation to help us understand the evolution and control of cancer. The students devote hours each week to the program, working individually and then meeting ...
The need for evolutionary theory in cancer research
This easy to read article by ACE's Amy M. Boddy, just published in European Journal of Epidemiology (2022), argues that even if we could understand all the mechanisms for cells to turn cancerous, it wouldn't be enough to help us treat and avoid the disease. For...
ACE Research paper in the journal Nature
Phenotypic plasticity and genetic control in colorectal cancer evolution is the second article by ACE researchers published in Nature on 26 October 2022. Here they show that genetic variation within a colorectal tumor doesn't often affect gene expression traits and...
Events
The Electric Life of Cancer – watch this amazing video
This is the second episode of our monthly ‘Cancer and the Nature of Life’ series. Mike Levin from Tufts University does an amazing job with ‘The Electric Life of Cancer’.
Watch Cancer and the Nature of Life Series
See this amazing talk: 'The Electric Life of Cancer' presented by Mike Levin with commentator, Paul Davies. Brief abstract: People once believed electricity was the spark of life. Now it’s been discovered that electrical effects do in fact help shape bodies and...
“Cancer and the Nature of Life” – New discussion series
ACE has a new discussion series about exciting themes in cancer research. It is suitable both for the public and for scientists. It will will take place monthly, on the third Friday of each month at 11 am PST (or noon on occasion). We are kicking off the series by...
San Antonio Breast Cancer Symposium
This major international conference from Dec 7th-10th 2021 will be hybrid this year. Participate in person at the Gonzalez Convention Center in San Antonio, Texas or watch online. Registration reopens 6th December.
Public Lecture with Sir Paul Nurse – Wednesday 24th March 2021 1pm MST, 4pm EST
Sir Paul Nurse, Director of the Crick Institute, London, is a Nobel prizewinning geneticist, former President of The Royal Society and of Rockerfeller University, and is Chief Scientific Advisor to the European Union. He will deliver the 2021 Beyond Annual Lecture...